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黄新安

时间:2018-09-25 16:42  作者: 文章来源: 点击:[]

 

黄新安博士,广州中医药大学热带医学研究所副研究员。从事植物化学和中医药信息学研究,主持完成国家自然科学基金、广东省自然科学基金和广州中医药大学高水平大学建设项目各1项,以及国家公派访问学者留学基金和中国政府派遣研究员项目

已发表论文:

[1]        Zhong, W. M.; Wang, J. F.; Wei, X. Y.; Chen, Y. C.; Fu, T. D.;  Xiang, Y.; Huang, X. A.; Tian, X. P.;  Xiao, Z. H.; Zhang, W. M.; Zhang, S.; Long, L .J .*; Wang F. Z.*. Variecolortins A-C, three pairs of spirocyclicdiketopiperazine enantiomers from the marine-derived fungus Eurotium sp. SCSIO F452. Org Lett, Epub: 16 July 2018,DOI:10.1021/acs.orglett.8b01880.

[2]        Liu, M. J.; Zhang, G. H.;Zheng, C. G.; Song, M.; Liu, F. L.; Huang, X. T.; Bai, S. S.; Huang, X. A.; Lin, C. Z.; Zhu, C. C.; Hu, Y. J.; Mi, S. Q.; Liu, C. H..*. Activating PXR by Imperatorin Attenuates Dextran Sulphate Sodium-Induced Colitis in Mice. Bri J Pharmaco, Epub: 26 June 2018, DOI:10.1111/bph.14424

[3]        Wang, L. T.; Jiang, W. M.; Shen, X.; Li, X. M.; Huang, X. A.;Xu, Z. L.; Sun, Y. M.; Chan, S. W.; Zeng, L. W.; Eremin, S. A.; Lei, H. T.*. Four hapten spacer sites modulating class specificity: Nondirectionalmultianalyte immunoassay for 31 βagonists and analogues. Anal. Chem., 2018, 90: 2716-2724.

[4]        Shen, X.;Chen, J. H.; Li, X. M.; Lei, H. T.*;Xu, Z. L.;Liu, Y. J.; Huang, X. A.;Eremin, S. A.; Wu, C. H.; Jia, A. J.*. Monoclonal antibody based homogeneous immunoassay for three banned agonists and molecular modeling insight. Food Agric. Immunol., 2017, 28(6): 1438-1449.

[5]        Zhang, Y. Q.; Wang, L. T.; Shen, X.; Wei, X. Q.;Huang, X. A.*; Liu, Y. J.*; Sun, X. L.; Wang, Z. H.; Sun, Y. M.; Xu, Z. L.; Eremin, S. A.; Lei, H. T.*. Broad-specificity immunoassay for simultaneous detection of ochratoxins A, B and C in millet and maize. J. Agric. Food Chem., 2017, 65(23): 4830-4838.

[6]        Chen, J. H.; Wang, L. T.; Lu, L. L.; Shen, X.; Huang, X. A.; Liu, Y. J.; Sun, X. L.; Wang, Z. H.; Eremin, S. A.; Sun, Y. M.; Xu, Z. L.; Lei, H. T.*. Four specific hapten conformations dominating antibody specificity: quantitative structure-activity relationship analysis for quinolone immunoassay. Anal. Chem., 2017, 89(12): 6740-6748.

[7]        Chen, J. H.; Lu, N.; Shen, X.; Tang, Q. S.; Zhang, C. J.; Xu, J.; Sun, Y. M.; Huang, X. A.*; Xu, Z. L.*; Lei, H. T.*.Investigation of an Immunoassay with Broad Specificity to Quinolone Drugs by Genetic Algorithm with Linear Assignment of Hypermolecular Alignment of Data Sets and Advanced Quantitative Structure–Activity Relationship Analysis. J. Agric. Food Chem., 2016, 64 (13): 2772-2779.

[8]        Zeng, H. P.; Chen, J. H.; Zhang, C. J.; Huang, X. A.*; Sun, Y. M.; Xu, Z. L.*; Lei, H. T.*. Broad-Specific chemiluminescence enzyme immunoassay for (fluoro)quinolones: hapten design and molecular modeling study of antibody recognition. Anal. Chem., 2016, 88 (7): 3909-3916.

[9]        Ji, S. S.; Dong, H. J.; Zhou, X. X.; Liu, Y. M.; Zhang, F. X.; Wang, Q.*; Huang, X. A.*. A structural hierarchy matching approach for molecular similarity/substructure searching. Molecules 2015, 20, 8791-8799.

[10]      Mu, H. T.; Wang, B. L.; Xu, Z. L.; Sun, Y. M.; Huang, X. A.; Shen Y. D.; Eremin, S.; Lei, H. T.*. Stereospecific recognition and quantitative structure-activity relationship between antibodies and enantiomers: ofloxacin as model hapten. Analyst, 2015, 140: 1037-1045.

[11]      Huang, X. A.; Shen, X. L.; Hu, Y. J.; Liu, Y. M.; Liu, K. L.; Zhang, F. X.*; Zhou, X. X.*. Two new triterpenoids from LysimachiaheterogeneaKlatt and evaluation of their cytotoxicity. Molecules, 2011, 16 (9): 8076-8082.

[12]      Huang, X. A.*; Liang, Y,J.;Cai, X. L.; Feng, X. Q.; Zhang, C. H.; Fu, L. W.; Deng, W. D. Four new cytotoxic oligosaccharidic derivatives of 12-oleanene from LysimachiaheterogeneaKlatt. Bioorg. Med. Chem. Lett., 2009, 19 (23): 6515-6518.

[13]      Huang, X. A.*; Jiang, H. Y.; Hao, G. Direct HPLC detection of benzodilactones and quinones in glands of Lysimachiafordiana. Fitoterapia, 2009, 80: 173-176.

[14]      15Fu, L. C.; Huang, X. A.*; Lai, Z. Y.; Hu, Y. J.; Liu, H. J.; Cai, X. L. A new 3-benzylchroman derivative from Sappan Lignum (Caesalpiniasappan). Molecules, 2008, 13: 1923-1930.

[15]      Hu, Y. J.; Shen, X. L.; Lu, H. L.; Zhang, Y. H.; Huang, X. A.; Fu, L. C.; Fong, W. F. Tenacigenin B derivatives reverse P-glycoprotein-mediated multidrug resistance in HepG2/Dox cells. J. Nat. Prod., 2008, 71: 1049-1051.

[16]      Huang, X. A.*; Ha, C. Y.; Yang, R. Z.; Jiang, H. Y.; Hu, Y. J.; Zhang, Y. H. A new alkaloid from Lysimachiapatungensis. Chem. Nat. Compd., 2007, 43: 170-172.

[17]      Huang, X. A.*; Yang, R. Z.; Cai, X. L.; Ye, S.; Hu, Y. J. Analysis of new benzo-di-lactones and quinones from LysimachiafordianaOliv. J. Mol. Struct., 2007, 830: 100-105.

[18]      Huang, X. A.*; Yang, R. Z.; Deng, W. D. A new poly-substituted benzaldehyde from the leaves of LysimachiafordianaOliv. Molecules, 2007, 12: 43-48.

[19]      Huang, X. A.; Yang, R. Z. A new hydroquinone diglucoside from Lysimachiafordiana. Chem. Nat. Compd., 2004, 40: 457-459.

 

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